In aerobic organisms, reactive oxygen species (ROS), such as hydroxide (OH), singlet oxygen (1O2), hydrogen peroxide (H2O2), and superoxide (O2–) ions are produced during aerobic respiration, which causes serious oxidative damage to biomolecules in the body. Hence, the removal of ROS, particularly O2–, is of primary importance as it reacts with H+ to produce other toxic ROS species like H2O2 and OH.

​In aerobic organisms, reactive oxygen species (ROS), such as hydroxide (OH), singlet oxygen (1O2), hydrogen peroxide (H2O2), and superoxide (O2–) ions are produced during aerobic respiration, which causes serious oxidative damage to biomolecules in the body. Hence, the removal of ROS, particularly O2–, is of primary importance as it reacts with H+ to produce other toxic ROS species like H2O2 and OH. Biochemistry Analytical Chemistry